| 货号:AG-20B-0069-C100 | 规格:100 ug | 目录价:¥4560 |
| 货号:AG-20B-0069-TRIAL | 规格:25 ug | 目录价:¥1740 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
anti-IL-36beta (human), mAb (Jacky-1) (25 ug)
别名:
Interleukin-36beta Interleukin-1 Family Member 8; IL-1F8
产品描述:
IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
宿主来源:
Purified from concentrated hybridoma tissue culture supernatant.
实验应用:
ELISA, WB
靶标/特异性:
Recognizes human IL-36beta. Does not cross-react with mouse IL-36beta and IL-36gamma.
同种型:
Mouse IgG1kappa
免疫原:
Recombinant human IL-36beta.
克隆号:
Jacky-1
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
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