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折扣/货期| 货号：AG-25B-0013-C050 | 规格：50 ug | 目录价：￥1320 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-Nod1 (human), pAb (AL184)
别名:
CARD4; Caspase Recruitment Domain-containing Protein 4; Nucleotide-binding Oligomerization Domain-containing Protein 1
产品描述:
Nod (CARD4) is a cytosolic pattern recognition molecule (PRRs) of the NLR (NOD-like receptor) family. Nod1 is widely expressed by many cell types and is implicated in sensing meso-diaminopimelic acid (meso-DAP)-containing PGN fragments, which are present in most Gramnegative bacteria and certain Gram-positive ones, like the Bacillus species. Upon activation, Nod1 initiates a pro-inflammatory response through NF-kappa signaling and is a key receptors in epithelial cells where it controls infections via the gastrointestinal system. Mutations in Nod1 have been reported to confer susceptibility to several inflammatory disorders including inflammatory bowel disease, atopic eczema and asthma.
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
Recognizes human Nod1.
免疫原:
Synthetic peptide corresponding to aa 2-31 (E2EQGHSEMEIIPSESHPHIQLLKSNRELLV31) of human Nod1.
产品浓度:
0.5 mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
产地:
瑞士
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