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折扣/货期| 货号：AG-25B-0015-C050 | 规格：50 ug | 目录价：￥2760 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-PIDD, pAb (AL233)
别名:
p53-induced Protein with a Death Domain; Leucine-rich Repeat and Death Domain-containing Protein; Lrdd
产品描述:
PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
宿主来源:
Rabbit
实验应用:
IHC, IP, WB
靶标/特异性:
Recognizes human and the native form of mouse PIDD. Detects bands of ~90kDa (Full Length FL-PIDD) and ~50kDa (cleaved protein) by Western blot.
免疫原:
Recombinant human PIDD (Death Domain: aa 776-910).
产品浓度:
1 mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
产地:
瑞士
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