anti-PD-1 (human), mAb (AG-IHC001)-单抗-深圳欣博盛生物科技有限公司

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anti-PD-1 (human), mAb (AG-IHC001)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20B-6020-R100

规格：100 ul

目录价：￥2280

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-PD-1 (human), mAb (AG-IHC001)

别名:

CD279; Programmed Cell Death Protein 1

产品描述:

Programmed Death 1 (PD-1) is a member of the CD28/CTLA-4 family of T cell regulators, expressed as a co-receptor on the surface of activated T cells, B cells and macrophages. Several studies have suggested that the PD-1/PD-L1 signaling pathway may be linked to antitumor immunity, as PD-L1 has been shown to induce apoptosis of activated T cells or inhibit activity of cytotoxic T cells. In comparison to CD10 and Bcl-6, PD-1 is expressed by fewer B cells and has therefore been considered a more specific and useful diagnostic marker for angioimmunoblastic T cell lymphoma. Therapies targeted toward the PD-1 receptor have shown remarkable clinical responses in patients with various types of cancer, including non-small-cell lung cancer, melanoma and renal-cell cancer. This antibody is intended to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods. It has been optimized and validated using the BOND-MAX fully automated IHC&ISH stainer (see Protocol).

宿主来源:

Purified from concentrated hybridoma tissue culture supernatant.

实验应用:

ELISA, IHC

靶标/特异性:

Recognizes human PD-1 (CD279).

同种型:

Mouse IgG2b

免疫原:

Recombinant human PD-1 fused to a His-tag.

克隆号:

AG-IHC001