anti-PSD-95, Rabbit Monoclonal (RM288)-单抗-深圳欣博盛生物科技有限公司

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anti-PSD-95, Rabbit Monoclonal (RM288)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：REV-31-1172-00-R100

规格：100 ul

目录价：￥5726

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-PSD-95, Rabbit Monoclonal (RM288)

别名:

Postsynaptic Density Protein 95; Disks Large Homolog 4; Synapse-associated Protein 90; SAP-90

产品描述:

PSD-95 is a member of proteins located at a specialized postsynaptic membrane region, called the postsynaptic density (PSD). PSD-95 is the most abundant scaffold protein specifically enriched in the PSD. It contains three PDZ domains, an SH3 domain and a guanylate kinase (GuK)-like domain. Through its PDZ domains, PSD-95 assembles various synaptic components at the PSD including intracellular signaling molecules (e.g. SynGAP and kalirin-7), ion channels (e.g. stargazin/AMPA receptors [AMPARs] and NMDA receptors) and cell adhesion molecules (e.g. neuroligin). PSD-95 plays a primary role in synaptic development and maturation and is regulated by palmitoylation at its N-terminal cysteine residues leading to its postsynaptic targeting. Palmitoylation of PSD-95 is triggered by DHHC2, a plasma membrane-inserted palmitoylating enzyme. Palmitoylated PSD-95 is almost exclusively localized at excitatory synapses in neurons.

宿主来源:

Rabbit

实验应用:

IHC, WB

靶标/特异性:

This antibody reacts to human and mouse PSD95. It may also react to rat PSD95, as predicted by immunogen homology.

同种型:

Rabbit IgG

免疫原:

A peptide corresponding to the N-terminus of human PSD95 .

克隆号:

RM288