| 货号:REV-31-1173-00-R100 | 规格:100 ul | 目录价:¥5726 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
anti-Vimentin (human), Rabbit Monoclonal (RM289)
产品描述:
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in mesenchymal cells. It is believed to be involved in the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During the development process, vimentin is exchanged for new, tissue-specific IFPs. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria and subsequent transport of cholesterol to the organelles lead to an increase in steroid synthesis. Vimentin has been used as a sarcoma tumor marker to identify mesenchyme.
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
This antibody reacts to human Vimentin. It may also react to mouse or rat Vimentin, as predicted by immunogen homology.
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to the C-terminus of human Vimentin.
.
克隆号:
RM289
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
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