| 货号:GTX04330 | 规格:100μg | 目录价:¥6600 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
APAF1 antibody
别名:
apoptotic peptidase activating factor 1 , APAF-1 , CED4
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA, FCM, WB
同种型:
IgG
免疫原:
E.coli-derived human APAF1 recombinant protein (Position: M1-E1248)
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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