| 货号:GTX16792 | 规格:50μg | 目录价:¥5900 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
APC antibody [FE9]
别名:
APC regulator of WNT signaling pathway , BTPS2 , DP2 , DP2.5 , DP3 , GS , PPP1R46
反应种属:
Human, Mouse, Rat
宿主来源:
Mouse
实验应用:
WB
靶标/特异性:
Reacts with all full-length and truncated APC proteins
同种型:
IgG1
免疫原:
Immunogen used was a synthetic peptide corresponding to the N-terminal 35 amino acid residues of APC.
克隆性:
Monoclonal
克隆号:
FE9
纯化方式:
Purified by chromatography over Protein G Sepharose followed by FPLC.
偶联:
Unconjugated
产品浓度:
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
预期分子量:
312
产品形式:
Liquid
存储溶液:
50mM Sodium Phosphate, 0.2% Gelatin, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008]
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