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折扣/货期| 货号：GTX23629 | 规格：100μg | 目录价：￥9200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Apc10 antibody
别名:
anaphase promoting complex subunit 10 , APC10 , DOC1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA, IHC, IP, WB
同种型:
IgG
免疫原:
Synthetic peptide corresponding to amino acids near the amino terminus of human APC10.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
1.5 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
生产商:
GeneTex
功能与背景:
APC is a ubiquitin ligase which specifically targets mitotic regulatory factors such as Pds 1/Cut 2 and cyclin B. It was found that APC 10/Doc 1 is localized in centrosomes and mitotic spindles throughout mitosis, while it is also localized in kinetochores from prophase to anaphase and in mid body in telophase and cytokinesis. These results strongly support the notion that human APC 10/Doc 1 may be one of the APC core subunits rather than the transiently associated regulatory factor.
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