APEX2 antibody, Internal-多抗-深圳欣博盛生物科技有限公司

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APEX2 antibody, Internal

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX80642

规格：400μl

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

APEX2 antibody, Internal

别名:

apurinic/apyrimidinic endodeoxyribonuclease 2 , APE2 , APEXL2 , XTH2 , ZGRF2

反应种属:

Human

宿主来源:

Rabbit

实验应用:

FCM, ICC/IF, IHC-P, WB

同种型:

IgG

免疫原:

KLH conjugated synthetic peptide between 143-171 amino acids from the Central region of human APEX2.

克隆性:

Polyclonal

克隆号:

纯化方式:

Protein A purified, followed by peptide affinity purification.

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 0.09% Sodium azide.

生产商:

GeneTex

功能与背景:

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]

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