| 货号:GTX15665 | 规格:100μg | 目录价:¥5300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Apolipoprotein B antibody [F2C3]
别名:
apolipoprotein B , FLDB , LDLCQ4 , apoB-100 , apoB-48
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, IHC-P, IP, RIA
同种型:
IgG2b
免疫原:
Purified human serum LDL
克隆性:
Monoclonal
克隆号:
F2C3
纯化方式:
Purified by ion exchange chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
10mM Potassium Phosphate, 135mM NaCl, 2.5mM KCl, 0.1% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]
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