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折扣/货期| 货号：GTX82848 | 规格：100μg | 目录价：￥5600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
APS antibody
别名:
SH2B adaptor protein 2 , Aps
反应种属:
Mouse
宿主来源:
Rabbit
实验应用:
ICC/IF, WB
同种型:
IgG
免疫原:
Synthetic peptide corresponding to residues E(605) A T L G R A R A V E N Q Y S(619) from mouse APS.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.1% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
APS (adapter protein with Pleckstrin homology and Src homology 2 domains) a member of the Lnk family, is an adaptor protein that is involved in B-cell signaling, insulin signaling, cytoskeletal reorganization. It is tyrosine phosphorylated by JAK2, KIT and other kinases during B-cell receptor stimulation of many different cytokines, chemokines and leukokines. APS has been shown to inhibit the JAK-STAT pathway in collaboration with c-Cbl. It is located in the cytoplasm in pre-PDGF (platelet derived growth factor) stimulated cells and localizes to the plasma membrane and peripheral regions upon PDGF stimulation. ? This protein is expressed in B-cells and mast cells when detected in haematopoietic cell lines yet is also expressed in many different tissues including spleen, prostrate, testis, uterus, small intestine and skeletal muscle.
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