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折扣/货期| 货号：AG-40T-0124-3010 | 规格：3 x 10 ug | 目录价：￥7500 |
| 货号：AG-40T-0124-C010 | 规格：10 ug | 目录价：￥3000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Arginase I (human) (rec.) (highly active) MultiPack
别名:
EC 3.5.3.1; ARG1; Arginase 1; Type I Arginase; Liver-type Arginase; L-Arginase
产品描述:
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Arginase is involved in the nitric oxide (NO) pathway and immune cell arginine metabolism. It is fundamentally involved in cancer, inflammation, infections, fibrotic diseases, neurobiology, pregnancy and immune regulation in general.
宿主来源:
E. coli
产品浓度:
0.2µg/µl
保存温度:
-20°C
运输温度:
DI
预期分子量:
34.7kDa
产品形式:
liquid
存储溶液:
Liquid. In 10mM TRIS-HCl, pH 7.5, containing 1mM beta-mercaptoethanol, 1mM MnCl2 and 50% glycerol.
有效期:
Stable for at least 1 year after receipt when stored at -80°C.
产地:
瑞士
纯度:
>90% (SDS-PAGE)
生物活性:
1.6 ±0.2U/µg protein. One unit is defined as the amount of enzyme that converts 1µmol of L-arginine to L-ornithine and urea per min. at 37°C, pH 9.5 (according to protocol from R.T. Schimke, et al.; J. Biol. Chem. 238, 1012 (1963)).
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