深圳欣博盛生物科技有限公司

RLR REPORTER CELLS

A549

(human)

A549-Dual™ KO-MDA5

NF-κB & IRFs, knockout of human MDA-5

SEAP / Lucia

a549d-komda5

A549-Dual™ KO-RIG-I 

NF-κB & IRFs, knockout of human   RIG-I 

SEAP / Lucia

a549d-korigi

A549-Dual™ KO-MAVS 

NF-κB & IRFs, knockout of human MAVS

SEAP / Lucia

a549d-komavs

RAW

(mouse)

RAW-Lucia™ ISG-KO-MDA5

IRFs, knockout of mouse MDA-5

Lucia

rawl-komda5

RAW-Lucia™ ISG-KO-RIG-I

IRFs, knockout of mouse RIG-I

Lucia

rawl-korigi

RAW-Lucia™ ISG-KO-MAVS

IRFs, knockout of mouse MAVS

Lucia

Lucia rawl-komavs

HEK293

(human)

HEK-Lucia™ RIG-I

IRFs, overexpression of human RIG-I

Lucia

hkl-hrigi

THP1

(human)

THP1-Dual KO MDA-5

NF-κB & IRFs, knockout of human MDA-5

SEAP / Lucia

thpd-komda5

THP1-Dual KO RIG-I

NF-κB & IRFs, knockout of human RIG-I

SEAP / Lucia

thpd-korigi

THP1-Dual KO MAVS

NF-κB & IRFs, knockout of human MAVS

SEAP / Lucia

thpd-komavs

B16
  (mouse)

B16-Blue™ISG-KO-STING

IRFs， knockout of mouse   STING

SEAP

bb-kostg

HE K 293
  (human)

HEK-Blue™ISG-KO-STING

IRFs， knockout of human   STING

SEAP

hkb-kostg

293-Dual™hSTING-A162

Double   readout**(IRFs&IFN-B) ， Lucia knocked into IFN-B
  S162A human STING transfected

SEAP/Lucia

293d-a162

293-Dual™hSTING-H232

Double   readout**(IRFs&IFN-β) ， Lucia   knocked into IFN-β,
  R71-G230-H232-R293 human STING transfected

SEAP/Lucia

293d-h232

HEK-Blue   STAT6-hSTING R232

STAT 6-specific   SEAP expression

SEAP

hkb-st6r232

293-Dual™hSTING-R232

Double   readout**(IRFs&IFN-β) ， Lucia   knocked into IFN-β，
  R71-G 230-R232-R293 human STING transfected

SEAP/Lucia

293d-r232

293-Dual™mSTING

Double   readout**(IRFs&IFN-β) ， Lucia   knocked into IFN-β
  mouse STING transfected

SEAP/Lucia

293d-mstg

RAW
  (mouse)

RAW-Lucia™IS G-KO-cGAS

IRFs， knockout of   mouse cGAS

Lucia

rawl-kocgas

RAW-Lucia™IS G-KO-IFI16

IRFs， knockout of   mouse IFI16

Lucia

rawl-koif16

RAW-Lucia™IS G-KO-STING

IRFs， knockout of mouse   STING

Lucia

raw-kostg

Raw-lucia IS   G-KO-TREX1

IRFs， knockout of   mouse TREX1

Lucia

rawl-kotrex

THP-1
  (human)

THP   1-Dual'KO-cGAS

NF-KB&IRFs， knockout of   human cGAS

SEAP/Lucia

thpd-kocgas

THP 1-Dual“KO-IFI16

NF-KB&IRFs， knockout of   human IFI16

SEAP/Lucia

thpd-koifi16

THP   1-Dual'KO-STING

NF-KB&IRFs， knockout of human   STING

SEAP/Lucia

thpd-kostg

THP   1-Dual'KI-hSTING-A162

NF-KB&IRFs， knockin of S162A   human STING
  (DMX A A sensitive isoform

SEAP/Lucia

thpd-a162

THP 1-Dual“KI-hSTING-H232

NF-KB&IRFs， knockin of R 71-G   230-H 232-R 293 human STING

SEAP/Lucia

thpd-h232

THP 1-Dual'KI   hSTING-M155

NF-KB&IRFs， knockin of V155M   human STING
  (constitutively active isoform)

SEAP/Lucia

thpd-m155

THP 1-Dual'KI-hSTING-R232

NF-KB&IRFs， knockin of R 71-G   230-R 232-R 293“wild-type'human STING

SEAP/Lucia

thpd-r232

THP 1-Dual'KI-h   STINGS154

NF-KB&IRFs， knockin of N154S   human STING
  (constitutively active isoform)

SEAP/Lucia

thpd-s154

THP 1-Dual'KI-m   STING

NF-KB&IRFs， knockin of mouse   STING

SEAP/Lucia

thpd-mstg

THP 1-Dual“KO-TREX1

NF-KB&IRFs， knockin of human   TREX 1

SEAP/Lucia

thpd-kotrex

CYTOSOLIC SENSORS OF   INTERMEDIATE METABOLITES OF LPS：ALPK1/TIFA

HE K-Blue'KO-ALPK   1

Knockout(KO) of   the ALPK1 gene

SEAP

hkb-koalpk

HE K-Blue'KO-TIFA

Knockout(KO) of   the TIFA gene

SEAP

hkb-kotifa