深圳欣博盛生物科技有限公司 a1

ASXL1 antibody
货号:GTX127284 规格:100μl 目录价:¥4000
货号:GTX127284-S 规格:25μl 目录价:¥1700
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ASXL1 antibody
别名:
ASXL transcriptional regulator 1 , BOPS , MDS
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
IHC-P, WB
靶标/特异性:
KO/KD validation is based on published data (PMID: 26385183).
同种型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the N-terminus region of human ASXL1. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 20% Glycerol, 0.01% Thimerosal.
生产商:
GeneTex
功能与背景:
This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
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