| 货号:GTX03187 | 规格:100μl | 目录价:¥5900 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ATF2 (phospho Thr71) antibody [GT1275]
别名:
activating transcription factor 2 , CRE-BP1 , CREB-2 , CREB2 , HB16 , TREB7
反应种属:
Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
A phospho specific peptide corresponding to residues surrounding T71 of human ATF2.
克隆性:
Monoclonal
克隆号:
GT1275
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
0.52 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
55
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]
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