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ATM antibody

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX22631

规格：50μl

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

ATM antibody

别名:

AT1 , ATA , ATC , ATD , ATDC , ATE , ATM , ATM serine/threonine kinase , TEL1 , TELO1

反应种属:

Human, Mouse

宿主来源:

Goat

实验应用:

IP, WB

同种型:

IgG

免疫原:

Synthetic peptide representing a portion of the protein encoded within exon 53 (LocusLink ID 472).

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

运输温度:

4°C

预期分子量:

351

产品形式:

Liquid

存储溶液:

Tris-Citrate/Phosphate, 0.1% Sodium azide.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]

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