| 货号:GTX70109 | 规格:100μl | 目录价:¥4300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ATR antibody [2B5]
别名:
ATR serine/threonine kinase , FCTCS , FRP1 , MEC1 , SCKL , SCKL1
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
Functional Assay, ICC/IF, IP, WB
同种型:
IgG1
免疫原:
Recombinant fragment, corresponding to amino acids 710-1100 of Human ATR.
克隆性:
Monoclonal
克隆号:
2B5
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
301
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
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