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折扣/货期| 货号：GTX631845-S | 规格：25μl | 目录价：￥1700 |
| 货号：GTX631845 | 规格：100μl | 目录价：￥4000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ATR (phospho Thr1989) antibody [GT222]
别名:
ATR serine/threonine kinase , FCTCS , FRP1 , MEC1 , SCKL , SCKL1
反应种属:
Human
宿主来源:
Mouse
实验应用:
ICC/IF, IP, WB
同种型:
IgG2b
免疫原:
Carrier-protein conjugated synthetic peptide surrounding phospho Thr1989 of human ATR. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
GT222
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
301
产品形式:
Liquid
存储溶液:
PBS, 20% Glycerol, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq]
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