ATRX Antibody / RAD54-单抗-深圳欣博盛生物科技有限公司

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ATRX Antibody / RAD54

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V3738IHC-7ML

规格：7 ml

目录价：￥6414.1

产品详情

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产品名称:

ATRX Antibody / RAD54

产品描述:

ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, it contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, it predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 Î± to mediate chromosomal segregation. Mutations in the gene correlate with a high incidence of severe X-linked form of syndromal mental retardation associated with alpha-thalassemia or ATRX syndrome

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG1, kappa

免疫原:

Recombinant human ATRX protein was used as the immunogen for this ATRX antibody.

克隆性:

Monoclonal (mouse origin)