p504S Antibody / AMACR-单抗-深圳欣博盛生物科技有限公司

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p504S Antibody / AMACR

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V8770-100UG

规格：100 ug

目录价：￥6652.1

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

p504S Antibody / AMACR

产品描述:

This antibody recognizes a protein of 44kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

IHC-P, WB

同种型:

Rabbit IgG

免疫原:

Full length human recombinant protein was used as the immunogen for the p504S antibody.

克隆性:

Rabbit Monoclonal