| 货号:GTX33595 | 规格:100μg | 目录价:¥9200 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
B-Raf (V600E Mutant Specific) antibody [RM8]
别名:
BRAF,BRAF1,BRaf protooncogene, serine/threonine kinase,Braf,NS7,RAFB1,B-Raf,B-Raf proto-oncogene, serine/threonine kinase
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA, ICC/IF, IHC-P, WB
靶标/特异性:
This antibody reacts to the BRAF V600E mutant. No cross reactivity with wild type BRAF.
同种型:
IgG
免疫原:
A peptide corresponding to BRAF V600E mutant
克隆性:
Monoclonal
克隆号:
RM8
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 50% Glycerol, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]
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