B7-H3 Antibody / CD276-单抗-深圳欣博盛生物科技有限公司

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B7-H3 Antibody / CD276

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V4055SAF-100UG

规格：100 ug

目录价：￥6414.1

产品详情

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产品名称:

B7-H3 Antibody / CD276

产品描述:

T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory molecules. One such molecule, B7-H3 (B7-homolog 3, also designated B7RP-2 and CD276) belongs to the B7 immunoglobulin superfamily. Soluble B7-H3 binds a putative receptor on activated T-cells that is distinct from CD28, CTLA-4, ICOS and PD-1. Widely expressed on nonlymphoid tissues, B7-H3 costimulates proliferation of both CD4+ and CD8+ T cells. The ability of B7-H3 to stimulate Th1 and cytotoxic-T cell responses suggest that it may have antitumor activity. B7-H3 interactions may play a role in regulating cell-mediated immune responses against cancer, implicating B7-H3 as a potential therapeutic tool.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG2b, kappa

免疫原:

A portion of amino acids 100-300 from the human CD276 protein was used as the immunogen for the B7-H3 antibody.

克隆性:

Monoclonal (mouse origin)