| 货号:GTX13805 | 规格:200μl | 目录价:¥5300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Bacillus anthracis Lethal Factor antibody
反应种属:
Bacillus anthracis
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
The antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 47-65 of the Anthrax LF protein (approx. 90 kD).
克隆性:
Polyclonal
克隆号:
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Serum diluted with PBS, 0.2% Gelatin, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family.
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