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折扣/货期| 货号：GTX25965 | 规格：100μg | 目录价：￥7200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BAFF Receptor antibody
别名:
BAFFR , BROMIX , CD268 , CVID4 , TNF receptor superfamily member 13C , TNFRSF13C , prolixin , BAFF Receptor
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
IHC, WB
同种型:
IgG
免疫原:
Peptide corresponding to aa 169-183 at the C-terminus of human BAFF-R.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
19
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
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