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折扣/货期| 货号：GTX642998 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX642998-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BAI1 antibody [HL4184]
别名:
adhesion G protein-coupled receptor B1 , BAI1 , GDAIF
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
This antibody is specific for the human BAI1 protein and does not cross-react with the human BAI2 and BAI3 proteins.<br>It detects both full-length BAI1 as well as the N-terminal fragment BAI1 form.<br>It was raised against human BAI1 Extracellular domain.
同种型:
IgG
免疫原:
Synthetic peptide encompassing a sequence within the Extracellular domain of human BAI1. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL4184
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008]
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