| 货号:GTX05007 | 规格:100μg | 目录价:¥7000 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BAP1 antibody [BAP1/8959R]
别名:
BAP1,BRCA1 associated protein 1,HUCEP13,UCHL2,hucep6
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
同种型:
IgG
免疫原:
Recombinant fragment (630-729 aa) of human BAP1 protein.
克隆性:
Monoclonal
克隆号:
BAP1/8959R
纯化方式:
Purified by Protein A/G
偶联:
Unconjugated
产品浓度:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA (Please contact us for PBS only format), 0.05% Sodium Azide.
生产商:
GeneTex
功能与背景:
This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
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