Bcl2A1 antibody-多抗-深圳欣博盛生物科技有限公司

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Bcl2A1 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX31738

规格：100μg

目录价：￥6200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Bcl2A1 antibody

别名:

BCL2 related protein A1 , ACC-1 , ACC-2 , ACC1 , ACC2 , BCL2L5 , BFL1 , GRS , HBPA1

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

ELISA, IHC-P, WB

靶标/特异性:

At least two isoforms are known to exist; this antibody will only detect the larger isoform.

同种型:

IgG

免疫原:

Bcl2A1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Bcl2A1.The immunogen is located within the last 50 amino acids of Bcl2A1.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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