深圳欣博盛生物科技有限公司 a1

Bestrophin antibody
货号:GTX14928 规格:100μg 目录价:¥6100
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Bestrophin antibody
别名:
bestrophin 1 , ARB , BEST , BMD , Best1V1Delta2 , RP50 , TU15B , VMD2
反应种属:
Human, Monkey, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ELISA, ICC/IF, IHC-P, IP, WB
同种型:
IgG
免疫原:
Mid-Region Synthetic peptide corresponding to unique amino acid sequences on human Bestrophin 1 protein.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
0.65 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
68
产品形式:
Liquid
存储溶液:
Tris/Glycine, 0.5% BSA, 30% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]
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