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折扣/货期| 货号：GTX01865 | 规格：500μl | 目录价：￥9400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
beta Catenin antibody [17C2]
别名:
catenin beta 1 , CTNNB , EVR7 , MRD19 , armadillo
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P
同种型:
IgG2a
免疫原:
Prokaryotic recombinant protein corresponding to a 160 amino acid region of the C-terminus of the beta-catenin molecule.
克隆性:
Monoclonal
克隆号:
17C2
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Tissue culture supernatant, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
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