| 货号:SIH-535-100MG | 规格:100 mg | 目录价:¥1972.8 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Bexarotene
别名:
SR 11247, Targretin, 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
产品描述:
Retinoid RXR agonist
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
348.5
产品形式:
White powder
产地:
加拿大
功能与背景:
Bexarotene is a highly potent and selective retinoid X receptor (RXR) agonist (1). Clinically useful antineoplastic agent for cutaneous T-cell lymphoma (2) Causes complete regression of mammary carcinoma (3). Bexarotene significantly increases clearance of soluble β-amyloid in a mouse Alzheimer′s model and increases cognitive ability (4). Reverses apoE4-driven brain pathology and behavioral deficits in vivo (5).
纯度:
>98% (TLC); NMR (Conforms)
来源:
Synthetic
CAS号:
153559-49-0
分子式:
C24H28O2
溶解度:
Soluble in DMSO (60 mg/ml) or ethanol (warm, 10 mg/ml)
PubChem CID:
82146
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