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折扣/货期| 货号：GTX60463 | 规格：100μl | 目录价：￥5800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BLNK antibody [5G9]
别名:
B cell linker , AGM4 , BASH , BLNK-S , LY57 , SLP-65 , SLP65 , bca
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
ELISA, FCM, ICC/IF, IHC-P, WB
同种型:
IgG1
免疫原:
Purified recombinant fragment of human BLNK expressed in E. Coli.
克隆性:
Monoclonal
克隆号:
5G9
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
50
产品形式:
Liquid
存储溶液:
Ascites, 0.03% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
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