BLNK antibody-多抗-深圳欣博盛生物科技有限公司

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BLNK antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX15008

规格：100μg

目录价：￥5000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

BLNK antibody

别名:

AGM4 , BASH , BLNK , BLNKS , Bcell linker , LY57 , SLP65 , bca , B cell linker

反应种属:

Mouse

宿主来源:

Rabbit

实验应用:

靶标/特异性:

This antibody reacts with mouse SLP65 / BLNK, a cytosolic adaptor protein identified as two phosphoproteins migrating at 68 and 70 kDa in SDS/PAGE (alternatively spliced forms of human SLP65).

同种型:

IgG

免疫原:

A fusion protein representing amino acids 171-356 of human BLNK.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by precipitation methods

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 15mM Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]

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