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折扣/货期| 货号：11-075 | 规格：50 mg | 目录价：￥5370 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Boceprevir
别名:
Victrelis; EBP 520; SCH 503034
保存温度:
Short Term Storage: +4C. Long Term Storage: -20C. Handling Advice: Keep cool and dry. Use/Stability: Stable for at least 2 years after receipt when stored at -20C.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
The antiviral agent boceprevir is a protease inhibitor that covalently and reversibly binds to the catalytic site (Ser139) of hepatitis C virus (HCV) nonstructural protein 3/4A (NS3/4A), a serine protease that is essential for viral replication (Ki = 14nM) by cleaving the virally encoded polyprotein into mature proteins like NS4A, NS4B, NS5A and NS5B. It inhibits the NS3/4A protease in an in vitro HCV replicon system with an EC50 value of 200 nM.
Boceprevir has been identified as a potential inhibitor of SARS-CoV-2 responsible for COVID-19. It inhibits SARS-CoV-2 viral replication by targeting the viral main protease Mpro (IC50 = 4.13µM).
纯度:
greater than or equal to 95% (NMR)
CAS号:
394730-60-0
分子式:
C27H45N5O5
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