官网链接
折扣/货期| 货号：11-076 | 规格：50 mg | 目录价：￥4738.5 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Clevudine
别名:
Levovir; L-FMAU; 2'-Fluoro-5-methyl-β-L-arabinofuranosyl-uracil
保存温度:
Short Term Storage: +4C. Long Term Storage: -20C. Handling Advice: Keep cool and dry. Use/Stability: Stable for at least 2 years after receipt when stored at -20C.
运输温度:
Blue Ice
产品形式:
Lyophilized
产地:
美国
生产商:
Prosci
功能与背景:
Clevudine is a synthetic pyrimidine nucleoside analog antiviral agent with activity against hepatitis B virus (HBV) and Epstein-Barr virus (EBV).
Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase and reverse transcriptase, consequently blocking the viral replication. It also blocks the DNA supply of the virus into the nucleus, reducing the amount of cccDNA by 20-100 times.
Potentially useful for the treatment of the SARS-CoV-2 (COVID-19) infection, acting as a potent inhibitor of the RdRp protein.
纯度:
greater than or equal to 98% (HPLC)
CAS号:
163252-36-6
分子式:
C10H13FN2O5
复制QQ号成功，请打开QQ后添加好友进行咨询