| 货号:GTX19276 | 规格:100μg | 目录价:¥9400 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BRD2 antibody
别名:
BRD2 , D6S113E , FSH , FSRG1 , NAT , O27.1.1 , RING3 , RNF3 , bromodomain containing 2
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
The specific epitope is in the region between aa 550 and 600 of human BRD2.
同种型:
IgG
免疫原:
Synthetic peptide representing a portion of the protein between the putative nuclear localization signal and the ET domain.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
预期分子量:
88
产品形式:
Liquid
存储溶液:
Tris-Citrate/Phosphate, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
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