BTNL2 (mouse):Fc (mouse) (rec.)-Fc融合蛋白-深圳欣博盛生物科技有限公司

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BTNL2 (mouse):Fc (mouse) (rec.)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CHI-MF-110BTNL2-C100

规格：100 ug

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

BTNL2 (mouse):Fc (mouse) (rec.)

别名:

Butyrophilin-like Protein 2

产品描述:

Butyrophilin-like 2 (BTNL2) is a butyrophilin family member with homology to the B7 costimulatory molecules, polymorphisms of which have been recently associated through genetic analysis; to sporadic inclusion body myositis and sarcoidosis. BTNL2 mRNA is highly expressed in lymphoid tissues as well as in intestine. BTNL2-Ig fusion protein was shown to recognize a putative receptor whose expression on B and T cells was significantly enhanced after activation. It inhibited T cell proliferation and TCR activation of NFAT, NF-kappaB and AP-1 signaling pathways. BTNL2 is the first member of the butyrophilin family that regulates T cell activation, which has implications in immune diseases and immunotherapy.

宿主来源:

CHO cells

保存温度:

+4°C

运输温度:

产品形式:

solid

存储溶液:

Lyophilized from 0.2µm-filtered solution in PBS.

有效期:

Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

产地: