官网链接
折扣/货期| 货号：GTX133980 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX133980-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
c-Abl (phospho Tyr245) antibody
别名:
c-abl oncogene 1, non-receptor tyrosine kinase , AI325092 , Abl , E430008G22Rik , c-Abl
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
This antibody is raised against mouse c-Abl (P00520-1) phosphorylated at Tyr226. Based on sequence homology, it is predicted to react with human c-Abl when phosphorylated at the corresponding residues - c-Abl (isoform a) Tyr226 or c-Abl (isoform b) Tyr245.
同种型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide surrounding phospho Tyr245 of mouse c-Abl. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
1.08 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
123
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
生产商:
GeneTex
功能与背景:
Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
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