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折扣/货期| 货号：GTX20032 | 规格：200μg | 目录价：￥2600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
c-Myc antibody [9E10]
别名:
MRTL,MYC,MYCC,bHLHe39,cMyc,vmyc avian myelocytomatosis viral oncogene homolog,cmyc,MYC proto-oncogene, bHLH transcription factor
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, FCM, ICC/IF, IP, WB
靶标/特异性:
This antibody recognizes the sequence EQKLISEEDL
同种型:
IgG1
免疫原:
Synthetic peptide sequence corresponding to the C-terminal region (residues 408-439) of human c-myc conjugated to keyhole limpet hemocyanin.
克隆性:
Monoclonal
克隆号:
90000000000
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
预期分子量:
49
产品形式:
Liquid
存储溶液:
Filter-sterilized PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
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