| 货号:GTX24216 | 规格:500μl | 目录价:¥5000 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
C4c / C4b antibody (FITC)
别名:
complement C4B (Chido blood group) , C4B1 , C4B12 , C4B2 , C4B3 , C4B5 , C4BD , C4B_2 , C4F , CH , CO4 , CPAMD3
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
靶标/特异性:
This antibody reacts with human C4, C4b and C4c but does not react with the C4d epitope.
同种型:
IgG
免疫原:
C4c complement isolated from complement activated human serum.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified IgG
偶联:
FITC
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. Protect from light.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. [provided by RefSeq, Jul 2008]
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