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折扣/货期| 货号：GTX25494 | 规格：200μl | 目录价：￥5600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Calmodulin antibody [6D4]
反应种属:
Bacteria, Bovine, Chicken, Human, Mouse, Rat
宿主来源:
Mouse
实验应用:
ELISA, ICC/IF, WB
靶标/特异性:
This antibody does not detect parvalbumin, tropinin, S-100, or myosin light chain kinase (MLCK). Addition of EGTA to buffers completely inhibits antibody staining.
同种型:
IgG1
免疫原:
Calmodulin purified from Dictyostelium discoideum.
克隆性:
Monoclonal
克隆号:
6D4
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Ascites, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
Calmodulin is a small, highly conserved calcium binding protein found in all eukaryotic cells. With the capacity to bind up to four calcium ions, this 17 kDa protein acts as an important intracellular receptor for regulatory calcium signals. As it binds calcium, calmodulin undergoes conformational changes which can increase its affinity for target proteins. It acts both directly, through interaction with key target enzymes, and indirectly, via specific kinases. Studies have found that calmodulin participates in the regulation of several biological processes including energy and biosynthetic metabolism, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of both cAMP and calcium concentrations.
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