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折扣/货期| 货号：GTX38806 | 规格：200μg | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Cardiac Troponin I antibody [19C7] (Biotin)
别名:
troponin I3, cardiac type , CMD1FF , CMD2A , CMH7 , RCM1 , TNNC1 , cTnI
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, Lateral Flow, WB
靶标/特异性:
Reacts equally with free cardiac troponin I (cTnI) and cTnI forming complexes with other troponincomponents. Not affected by heparin, phosphorylation and oxidation. Recognizes an epitope locatedbetween amino acid residues 41 and 49 of cTnI. No cross-reactivity with skeletal muscle troponin I.Reactive with cTnI from human, monkey, bovine, porcine, goat, canine, rabbit, feline, rat, mouse and fish.
同种型:
IgG2b
免疫原:
Native Troponin Complex
克隆性:
Monoclonal
克隆号:
19C7
纯化方式:
Protein A purified
偶联:
Biotin
产品浓度:
1.40 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
20mM Tris-HCl, 150mM NaCl, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
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