官网链接
折扣/货期| 货号：GTX106820 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX106820-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CBFb antibody [N1C3]
别名:
core-binding factor subunit beta , PEBP2B
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the center region of human CBFb. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
22
产品形式:
Liquid
存储溶液:
0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
您可能感兴趣的产品
WDR24 antibody
货号：GTX133576
Avian Influenza A virus H9N2 HA (Hemagglutinin) antibody
货号：GTX127306
Influenza A virus M2 (matrix protein) antibody
货号：GTX125951
Acta2 antibody
货号：GTX124505
MCTS1 antibody [N1C3]
货号：GTX117793
MAFG antibody
货号：GTX114541
Golgin 97 antibody [C2C3], C-term
货号：GTX114445
Aconitase 2 antibody [N1N3]
货号：GTX114233
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询