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折扣/货期| 货号：GTX640123-S | 规格：25μl | 目录价：￥1700 |
| 货号：GTX640123 | 规格：100μl | 目录价：￥4000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CCR10 antibody [HL2852]
别名:
C-C motif chemokine receptor 10 , GPR2
反应种属:
Human
宿主来源:
Rabbit
实验应用:
Functional Assay, ICC/IF
靶标/特异性:
This antibody is specific for human CCR10 protein and does not cross react with human CCR1, CCR2, CCR4, CCR5, CCR7, and CCR9 protein.<br>This antibody was raised against human CCR10 Extracellular domain.
同种型:
IgG
免疫原:
Synthetic peptide encompassing a sequence within the Extracellular domain human of CCR10. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL2852
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]
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