深圳欣博盛生物科技有限公司 a1

货号:GTX640124 规格:100μg 目录价:¥4000
货号:GTX640124-S 规格:100μg 目录价:¥1700
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CCR10 antibody [HL2853]
别名:
DExD/H-box helicase 58 , RIG-I , RIG1 , RIGI , RLR-1 , SGMRT2
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ELISA, ICC/IF, IHC-P, WB
同种型:
IgG
免疫原:
DDX58 antibody was raised against human GST-tagged DDX58 protein.
克隆性:
Polyclonal
克隆号:
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
107
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the cytoplasmic helicase retinoic acid inducible gene protein 1 (RIG-1) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. Unlike TLR3 however, RIG-1 activates the kinases TBK1 and IKKepsilon through the adaptor protein IPS-1. These kinases then phosphorylate the transcription factors IRF-3 and IRF-7 which are essential for the expression of type-I interferons. RIG-1 is required for the production of interferons in response to RNA viruses including paramyxoviruses, influenza virus, and Japanese encephalitis virus.
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