CCR3 antibody-多抗-深圳欣博盛生物科技有限公司

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CCR3 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX21667

规格：100μg

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CCR3 antibody

别名:

CC motif chemokine receptor 3,CCCKR3,CCR3,CD193,CKR3,CMKBR3,C-C motif chemokine receptor 3

反应种属:

Human

宿主来源:

Goat

实验应用:

ELISA, ICC/IF, IHC, WB

靶标/特异性:

Peptide sequence is < 50 % identical to other human chemokine receptors in this region.

同种型:

IgG

免疫原:

C-VETFGTTSYYDDVGLLCEKADTRALMA 28 amino acid synthetized corresponding to aa 8-34 (cysteine added for coupling) of the N-terminal domain of human CCR3

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

10mM KHPO₄, 140mM NaCl, 0.1% BSA, 0.1% Sodium azide.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]

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