| 货号:SIH-185-10MG | 规格:10 mg | 目录价:¥5803.2 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
CCT196969
别名:
1-(3-(tert-butyl)-1-phenyl-1H-pyrazol-5-yl)-3-(2-fluoro-4-((3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yl)oxy)phenyl)urea, CCT-196969, CCT 196969
产品描述:
RAF Inhibitor
保存温度:
-20ºC
运输温度:
Blue Ice or 4ºC
预期分子量:
513.53
产品形式:
White Solid
产地:
加拿大
功能与背景:
CCT196969, a pan-RAF/SFK inhibitor is active against treatment-naive BRAF and NRAS mutant melanoma tumors. It is also active in tumors from patients who developed resistance to BRAF-selective inhibitors and a BRAF plus MEK inhibitor combination. IC50 0.1µM and 0.03µM for BRAF kinase and SRC kinase respectively.
纯度:
96%
来源:
Synthetic
CAS号:
1163719-56-9
分子式:
C27H24FN7O3
溶解度:
Soluble in DMSO
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