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折扣/货期| 货号：CHI-HF-211CD134-C100 | 规格：100 ug | 目录价：￥5040 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD134 [OX40] (human):Fc (mouse) (rec.)
别名:
OX40; Tumor Necrosis Factor Receptor Superfamily Member 4; TNFRSF4; ACT35; TXGP1L
产品描述:
CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen CD27, B cell antigen CD40, FAS antigen and the T cell activation antigen 4-1BB. The human CD134 protein is expressed only on activated CD4+ T blasts, and its ligand has been identified as gp34. Interactions between CD134 and its ligand in vivo are necessary for the differentiation of activated B cells into highly immunoglobulin-producing cells, however not involved in other pathways of antigen-driven differentiation of B cells such as development of memory cells in the germinal centers. In addition, the CD134 and gp34 system directly mediate adhesion of activated T cells to vascular endothelial cells, and contribute to growth stimulation of the virus-infected T cells.
宿主来源:
HEK 293 cells
保存温度:
+4°C
运输温度:
BI
预期分子量:
~65kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
生物活性:
Measured by its binding ability in a functional ELISA.
内毒素水平:
<5EU/mg protein (LAL test; Lonza).
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