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折扣/货期| 货号：GTX31047 | 规格：100μg | 目录价：￥4800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD16 antibody [3G8]
别名:
Fc fragment of IgG receptor IIIa , CD16 , CD16A , FCG3 , FCGR3 , FCGRIII , FCR-10 , FCRIII , FCRIIIA , IGFR3 , IMD20
反应种属:
Human, Primate, Rhesus Monkey
宿主来源:
Mouse
实验应用:
ELISA, FCM, IHC, IHC-Fr, IP, Neutralizing/Inhibition
同种型:
IgG1
免疫原:
Human neutrophils
克隆性:
Monoclonal
克隆号:
3G8
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 15mM Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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