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折扣/货期| 货号：GTX20664-00 | 规格：100μg | 目录价：￥4700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CD16 antibody [MEM-154] (Low Endotoxin)
别名:
CD16 , CD16A , FCG3 , FCGR3 , FCGR3A , FCGRIII , FCR10 , FCRIII , FCRIIIA , Fc fragment of IgG receptor IIIa , IGFR3 , IMD20 , CD16a
反应种属:
Human
宿主来源:
Mouse
实验应用:
FCM, Functional Assay, IP, WB
靶标/特异性:
This antibody reacts with an epitope on CD16 antigen that is residing in proximity to FG loop (probably BC or C'E loop).
同种型:
IgG1
免疫原:
Human granulocytes
克隆性:
Monoclonal
克隆号:
MEM-154
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
预期分子量:
29
产品形式:
Liquid
存储溶液:
Filter-sterilized PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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